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Kasturba Hospital started in 1944 in Sevagarm and Kasturba Nursing School was established in 1973. At that time there was acute shortage of nursing teachers and administrative nursing personnel. There was no nursing college in Vidarbha region. It was the dream of Dr. Sushila Nayar to start nursing college in rural area, therefore Kasturba Health Society decided that nursing college should be started at our institution itself.

Kasturba Nursing College Sevagram was established in 1997. The foundation stone was laid by Dr. Shankar Dayal Sharma, vice president of India on 30-12-1990 and the building was inaugurated by Hon. Then president of India Dr. Shankar Dayal Sharma on 15-2-1993. 
The enthusiasm and hard work put in by Dr. Sushila Nayar and her dedicated colleagues made it possible to start nursing college admitting the 1st batch of Post Certificate B.Sc. Nursing students in 1997 with an annual intake of 10 students. In 2006 Post Certificate B.Sc. Nursing was renamed as Post Basic B.Sc. Nursing.  Later in 2007 intake capacity was increased to 20 students per year.

This college is 20 years old now. New courses were added to it. In 2008 Basic B.Sc. Nursing course was started with 40 annual intake and in 2011 Post Graduates M.Sc. Nursing started in 4 specialties. viz. Medical surgical nursing, Community health nursing, Obstetric and Gynecological nursing and Mental health nursing with 5 students in each specialty.

In 2016 Kasturba Nursing College is identified by Ministry of Health and Family welfare, Gov. of India, as a National Nodal Centre to Conduct 6 weeks training programme on ‘Strengthening Pre-Service Nursing Midwifery Education’. National Nodal Centre, Wardha caters 5 stats of India i.e. Maharashtra, Goa, Telangana, Chattisgrah, and Madya Pradesh. First batch of training was started in March 2016.